Regulation of NADPH oxidases is conserved between plants and animals

In collaboration with USA, Japan, and Finland we carried out a detailed structural analysis of critical plant and animal enzymes –  NADPH oxidases. We discovered far greater conservation of their activity but significantly also in their regulation than previously assumed.

This information will enable further comparative studies and open up novel aspects of how plant NADPH oxidase activity is controlled in plants in response to environmental cues and plant growth and development.

Cooperating entity: UC Davis, USA; Ritsumeikan University, Japn; University of Helsinki, Finland
Publication: Castro B, Citterico M, Kimura S, Stevens D, Wrzaczek M*, Coaker GL. 2021. Stress-induced reactive oxygen species compartmentalization, perception and signalling. Nature Plants 7: 403-412.