HR Excellence in Science

Mgr. Jan Kotál

Position PhD student - Laboratory of Genomics and Proteomics of Disease Vectors
Tick-Borne Diseases
Institute of Parasitology

Contact details +420 387775492
jankotal@gmail.com
215

Others

Education

Faculty of Science, University of South Bohemia

  • Bachelor's thesis: Towards the functional characterization of a "cysteine rich" protein family member from Ixodes ricinus. Defended: June 2011
  • Master thesis (since March 2012): Tick regulators of vertebrate proteolysis (Supervisor: Michalis Kotsyfakis; consultant: Alexandra Schwarz)

Total found: 14 records
Chlastáková A., Kotál J., Beránková Z., Kaščáková B. , Martins L., Langhansová H., Ederová M., Kutá Smatanová I., Kotsyfakis M., Chmelař J. (2021) Iripin-3, a New Salivary Protein Isolated From Ixodes ricinus Ticks, Displays Immunomodulatory and Anti-Hemostatic Properties In Vitro Frontiers in Immunology 12: 626200.
DOI: 10.3389/fimmu.2021.626200
Kaščáková B. , Kotál J., Martins L., Beránková Z., Langhansová H., Calvo E., Crossley J.A., Havlíčková P., Dycka F., Prudnikova T., Kutý M., Kotsyfakis M., Chmelař J., Kutá Smatanová I. (2021) Structural and biochemical characterization of the novel serpin Iripin-5 from Ixodes ricinus Acta Crystallographica Section D-Structural Biology D77: 1183-1196.
DOI: 10.1107/S2059798321007920
Kotál J., Buša M., Urbanová V., Řezáčová P., Chmelař J., Langhansová H., Sojka D., Mareš M., Kotsyfakis M. (2021) Mialostatin, a Novel Midgut Cystatin from Ixodes ricinus Ticks: Crystal Structure and Regulation of Host Blood Digestion International Journal of Molecular Sciences 22: 5371.
DOI: 10.3390/ijms22105371
Kotál J., Polderdijk S.G.I., Langhansová H., Ederová M., Martins L., Beránková Z., Chlastáková A., Hajdušek O., Kotsyfakis M., Huntington J.A., Chmelař J. (2021) Ixodes ricinus salivary serpin iripin-8 inhibits the intrinsic pathway of coagulation and complement International Journal of Molecular Sciences 22: 9480.
DOI: 10.3390/ijms22179480
Martins L., Bensaoud C., Kotál J., Chmelař J., Kotsyfakis M. (2021) Tick salivary gland transcriptomics and proteomics Parasite Immunology 43: e12807.
DOI: 10.1111/pim.12807
Martins L., Kotál J., Bensaoud C., Chmelař J., Kotsyfakis M. (2020) Small protease inhibitors in tick saliva and salivary glands and their role in tick-host-pathogen interactions BBA - Proteins and Proteomics 1868: 140336.
DOI: 10.1016/j.bbapap.2019.140336
Chmelař J., Kotál J., Kovaříková A., Kotsyfakis M. (2019) The Use of Tick Salivary Proteins as Novel Therapeutics Frontiers in Physiology 10: 812.
DOI: 10.3389/fphys.2019.00812
Kotál J., Stergiou N., Buša M., Chlastáková A., Beránková Z., Řezáčová P., Langhansová H., Schwarz A., Calvo E., Kopecký J., Mareš M., Schmitt E., Chmelař J., Kotsyfakis M. (2019) The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin Cellular and Molecular Life Sciences 76: 2003–2013.
DOI: 10.1007/s00018-019-03034-3
Perner J., Kotál J., Hatalová T., Urbanová V., Bartošová-Sojková P., Brophy P.M., Kopáček P. (2018) Inducible glutathione S-transferase (IrGST1) from the tick Ixodes ricinus is a haem-binding protein Insect Biochemistry and Molecular Biology DOI: 10.1016/j.ibmb.2018.02.002
Chmelař J., Kotál J., Langhansová H., Kotsyfakis M. (2017) Protease inhibitors in tick saliva: the role of serpins and cystatins in tick-host-pathogen interaction Frontiers in Cellular and Infection Microbiology 7: 216.
DOI: 10.3389/fcimb.2017.00216
Chmelař J., Kotál J., Karim S., Kopáček P., Francischetti I., Pedra J., Kotsyfakis M. (2016) Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions Trends in Parasitology 32: 242-254.
DOI: 10.1016/j.pt.2015.10.002
Chmelař J., Kotál J., Kopecký J., Pedra J., Kotsyfakis M. (2016) All for one and one for all on the tick–host battlefield Trends in Parasitology 32: 368-377.
DOI: 10.1016/j.pt.2016.01.004
Klein M., Brühl T., Staudt V., Reuter S., Grebe N., Gerlitzki B., Hoffmann M., Bohn T., Ulges A., Stergiou N., De Graaf J., Löwer M., Taube C., Becker M., Hain T., Dietzen S., Stassen M., Huber M., Lohoff M., Campos Chagas A., Andersen J., Kotál J., Langhansová H., Kopecký J., Schild H., Kotsyfakis M., Schmitt E., Bopp T. (2015) Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast Cells The Journal of Immunology 195: 621-631.
DOI: 10.4049/jimmunol.1401823
Kotál J., Langhansová H., Lieskovská J., Andersen J., Francischetti I., Chavakis T., Kopecký J., Pedra J., Kotsyfakis M., Chmelař J. (2015) Modulation of host immunity by tick saliva Journal of Proteomics 128: 58-68.
DOI: 10.1016/j.jprot.2015.07.005

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Biology Centre CAS
Branišovská 1160/31
370 05 České Budějovice
Data box: r84nds8

 

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