HR Excellence in Science

RNDr. Zuzana Lhotská

Position 1 PhD Student - Laboratory of parasitic therapy
Opportunistic Disease
Institute of Parasitology

Position 2 Technician - Laboratory of parasitic therapy
Opportunistic Disease
Institute of Parasitology

Contact details +420 38 777 5420
zuzana.lhotska@paru.cas.cz
132

Others

Brief Profile

Zuzana decided in the first year of university studies (University of South Bohemia – USB) to perform her bachelor and then her master thesis in the Laboratory of Parasitic Therapy (BC CAS). There, she focused her research on the gut protist Blastocystis which role in human health is still unclear. During her undergraduate studies, she received two grants from the Student Grant Agency of USB, which she successfully defended. The first project associated with the bachelor topic was focused on in vitro axenization of Blastocystis and in the second project (in the master study) on the epidemiological study with emphasis on the occurrence of Blastocystis in gut-healthy human population in the Czech Republic. Zuzana also participated in other Blastocystis laboratory projects. She is currently a PhD student and is still involved in Blastocystis research (functional changes in genome during host colonization).


Education:
  • 8/2019 – present: Ph.D. student; University of South Bohemia (USB; Faculty of Science) and Biology Centre of the Czech Academy of Sciences (BC CAS); program - Infectious Biology
  • 2019: State rigorous exam in Parasitology (=RNDr. – doctor of life sciences)
  • 9/2017 – 6/2019: master studies at USB; program - Parasitology
  • 9/2013 – 6/2017: bachelor studies at USB; program - Biology
  • 2009 – 2013: Secondary Vocational School of Veterinary, Mechanization and Horticulture - veterinary field
Career outline:
  • 1/2020 – present: PhD position, Laboratory of Parasitic Therapy; Institute of Parasitology (BC CAS)
  • 12/2014 – 12/2019: technician, Laboratory of Parasitic Therapy; Institute of Parasitology (BC CAS)
  • 9/2017 – 6/2019: diploma thesis, Laboratory of Parasitic Therapy (BC CAS) entitled 'Study of Blastocystis in human microbiome'
  • 9/2013 – 6/2017: bachelor thesis in the Laboratory of Parasitic Therapy (BC CAS) entitled 'Axenization of intestinal protist of the genus Blastocystis'
Further work experience: 
  • molecular biology, molecular diagnostics and cloning (gained within master studies)
  • sequences, sequence alignments and phylogeny (gained within master studies)
  • experimental work with laboratory animals 
  • axenic and xenic cultivation methods for intestinal protozoa
  • coproscopic techniques for the detection of intestinal parasites
  • non-invasive sampling and other common laboratory methods

Projects & internship

  • 2018: PI of the project supported by the Student Grant Agency (SGA) of the Faculty of Science of USB, entitled 'Study of Blastocystis in Human Microbiome'
  • 6 –7/2017: a short-term internship at the University of British Columbia (Canada): CD4 T-cell transfer model of colitis; Department of Microbiology and Immunology; under the direction of Lisa Osborne Ph.D.;
  • 2015: PI of the project supported by the Student Grant Agency (SGA) of the Faculty of Science of the USB, entitled 'Introduction of a Suitable Experimental in vitro Model for the Study of Intestinal Protozoa of the Genus Blastocystis¨

Supplementary education: 

  • 2020 –The Workshop on Genomics in Český Krumlov

Total found: 7 records
Brožová K., Jirků M., Lhotská Z., Květoňová D., Kadlecová O., Rune Stensvold C., Samaš P., Petrželková K. J., Jirků-Pomajbíková K. (2023) The Opportunistic Protist, Giardia intestinalis, Occurs in Gut-healthy Humans in a High-income Country Giardia intestinalis in gut-healthy humans Emerging Microbes and Infections 12: 2270077.
DOI: 10.1080/22221751.2023.2270077
Jirků M., Kašparová A., Lhotská Z., Oborník M., Brožová K., Petrželková K. J., Samaš P., Kadlecová O., Stensvold C., Jirků-Pomajbíková K. (2022) A cross-sectional study on the occurrence of the intestinal protist, Dientamoeba fragilis, in the gut-gealthy volunteers and their animals International Journal of Molecular Sciences 22: 15407.
DOI: 10.3390/ijms232315407
Šloufová M., Lhotská Z., Jirků M., Petrželková K. J., Stensvold C., Cinek O., Jirků-Pomajbíková K. (2022) Comparison of molecular diagnostic approaches for the detection and differentiation of the intestinal protist Blastocystis sp. in humans Parasite 29: 30.
DOI: 10.1051/parasite/2022029
Billy V., Lhotská Z., Jirků M., Kadlecová O., Frgelecová L., Wegener Parfrey L., Jirků-Pomajbíková K. (2021) Blastocystis Colonization Alters the Gut Microbiome and, in Some Cases, Promotes Faster Recovery From Induced Colitis Frontiers in Microbiology 2: 641483.
DOI: 10.3389/fmicb.2021.641483
Jirků M., Lhotská Z., Frgelecová L., Kadlecová O., Petrželková K. J., Morien E., Jirků-Pomajbíková K. (2021) Helminth Interactions with Bacteria in the Host Gut Are Essential for Its Immunomodulatory Effect Microorganisms 9: 226.
DOI: 10.3390/microorganisms9020226
Lhotská Z., Jirků M., Hložková O., Brožová K., Jirsová D., Stensvold C., Kolísko M., Jirků-Pomajbíková K. (2020) A Study on the Prevalence and Subtype Diversity of the Intestinal Protist Blastocystis sp. in a Gut-Healthy Human Population in the Czech Republic Frontiers in Cellular and Infection Microbiology 10: 544335.
DOI: 10.3389/fcimb.2020.544335
Růžková J. , Květoňová D., Jirků M., Lhotská Z., Stensvold C., Wegner Parfrey L., Jirků-Pomajbíková K. (2018) Evaluating rodent experimental models for studies of Blastocystis ST1 Experimental Parasitology 191: 55–61.
DOI: 10.1016/j.exppara.2018.06.009

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Biology Centre CAS
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370 05 České Budějovice
Data box: r84nds8

 

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