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Chauhan P., Panicucci Zíková A. (2022) Mechanisms and players of mitoribosomal biogenesis revealed in trypanosomatids Trends in Parasitology
38: 1053-1067.
DOI: 10.1016/j.pt.2022.08.010
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Gahura O., Mühleip A.,
Hierro-Yap C.,
Panicucci B.,
Jain M., Hollaus D.,
Slapničková M., Panicucci Zíková A., Amunts A. (2022) An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases Nature Communications
13: 5989.
DOI: 10.1038/s41467-022-33588-z
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Klejch T., Keough D., King G.,
Doleželová E., Česnek M., Buděšínský M., Panicucci Zíková A., Janeba Z., Guddat L., Hocková D. (2022) Stereo-defined acyclic nucleoside phosphonates are selective and potent inhibitors of parasite 6-oxopurine phosphoribosyltransferases Journal of Medicinal Chemistry
65: 4030–4057.
DOI: 10.1021/acs.jmedchem.1c01881
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Lemke C., Jílková A., Ferber D., Braune A., On A., Johe P., Panicucci Zíková A., Schirmeister T., Mareš M., Horn M., Gütschow M. (2022) Two Tags in One Probe: Combining Fluorescence- and Biotin-based Detection of the Trypanosomal Cysteine Protease Rhodesain Chemistry-A European Journal
28: e202201636.
DOI: 10.1002/chem.202201636
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Panicucci Zíková A. (2022) Mitochondrial adaptations throughout the Trypanosoma brucei life cycle Journal of Eukaryotic Microbiology
69: e12911.
DOI: 10.1111/jeu.12911
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Štěpánek O., Čmoková A., Procházková E. , Grobárová V., Černý J.,
Slapničková M., Panicucci Zíková A., Kolařík M., Baszczyňski O. (2022) Piperazine-Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens ChemMedChem
17: e202200385.
DOI: 10.1002/cmdc.202200385
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Vaňková K.,
Doleželová E., Tloušťová E., Hocková D., Panicucci Zíková A., Janeba Z. (2022) Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase European Journal of Medicinal Chemistry
239: 114559.
DOI: 10.1016/j.ejmech.2022.114559
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Cadena L.,
Gahura O.,
Panicucci B., Panicucci Zíková A.,
Hashimi H. (2021) Mitochondrial Contact Site and Cristae Organization System and F1FO-ATP Synthase Crosstalk Is a Fundamental Property of Mitochondrial Cristae mSphere
16: e0032721.
DOI: 10.1128/mSphere.00327-21
Dokumenty ke stažení:
Cadena_2021_mSphere (pdf)
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Doleželová E., Klejch T., Špaček P., Slapničková M., Guddat L., Hocková D., Zíková A. (2021) Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro Scientific Reports
11: 13317.
DOI: 10.1038/s41598-021-91747-6
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Gahura O.,
Hierro-Yap C., Zíková A. (2021) Redesigned and reversed: architectural and functional oddities of the trypanosomal ATP synthase Parasitology
148: 1151–1160.
DOI: 10.1017/S0031182021000202
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Hierro-Yap C., Šubrtová ,
Gahura O.,
Panicucci B., Dewar C., Chinopoulos C., Schnaufer A., Zíková A. (2021) Bioenergetic consequences of FoF1-ATP synthase/ATPase deficiency in two life cycle stages of Trypanosoma brucei Journal of Biological Chemistry
296: 100357.
DOI: 10.1016/j.jbc.2021.100357
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Kalčic F., Frydrych J.,
Doleželová E.,
Slapničková M., Pachl P., Slavětínská L.P., Hocková D., Zíková A., Janeba Z. (2021) C1'-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase European Journal of Medicinal Chemistry
225: 113798.
DOI: 10.1016/j.ejmech.2021.113798
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Nguyen V.H., Tichý M., Rožánková S., Pohl R.,
Doleželová E., Tloušťová E.,
Slapničková M., Zíková A., Hocek M. (2021) Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides Bioorganic & Medicinal Chemistry Letters
40: 127957.
DOI: 10.1016/j.bmcl.2021.127957
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Perlíková P., Krajczyk A.,
Doleželová E.,
Slapničková M., Milisavljevic N., Slavětínská L.P., Tloušt'ová E., Gurská S., Džubák P., Hajdúch M., Panicucci Zíková A., Hocek M. (2021) Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides ACS Infectious Diseases
7: 917–926.
DOI: 10.1021/acsinfecdis.1c00062
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Serricchio M.,
Hierro-Yap C., Schädeli D., Hamidane H.B., Hemphill A., Graumann J., Panicucci Zíková A., Bütikofer P. (2021) Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms Faseb Journal
35: e21176.
DOI: 10.1096/fj.202001579RR
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Tobiasson V.,
Gahura O., Aibara S., Baradaran R., Panicucci Zíková A., Amunts A. (2021) Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit Embo Journal
e106292.
DOI: 10.1101/2020.06.28.176446
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Villafraz O., Biran M., Pineda E., Plazolles N., Cahoreau E., Ornitz Oliveira Souza R., Thonnus M., Allmann S., Tetaud E., Rivière L., Silber A.M., Barrett M.P., Zíková A., Boshart M., Portais J.C., Bringaud F. (2021) Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline PLoS Pathogens
17: 1009204.
DOI: 10.1371/journal.ppat.1009204
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Aphasizheva I., Alfonzo J., Carnes J., Cruz-Reyes J., Göringer H.U., Hajduk S.,
Lukeš J., Madison-Antenucci S., Maslov D., Mcdermott S., Ochsenreiter T., Read L., Salavati R., Schnaufer A., Schneider A., Simpson L., Stuart K., Yurchenko V., Zhou Z.H., Panicucci Zíková A., Zhang L., Zimmer S., Aphasizhev R. (2020) Lexis and Grammar of Mitochondrial RNAProcessing in Trypanosomes Trends in Parasitology
36: 4.
DOI: 10.1016/j.pt.2020.01.006
Dokumenty ke stažení:
Aphasizheva_2020_TrendsinParasitology (pdf)
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Doleželová E.,
Kunzová M., Dejung M., Levin M.,
Panicucci B., Regnault C., Janzen C., Barrett M.P., Butter F., Panicucci Zíková A. (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei Plos Biology
18: e3000741.
DOI: 10.1371/journal.pbio.3000741
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Smith J.T.,
Doleželová E., Tylec B., Bard J.E., Chen R., Sun Y., Panicucci Zíková A., Read L. (2020) Developmental regulation of edited CYb and COIII mitochondrial mRNAs is achieved by distinct mechanisms in Trypanosoma brucei Nucleic Acids Research
48: 8704–8723.
DOI: 10.1093/nar/gkaa641
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