RNDr. Petr Šimek, CSc.
Vedoucí laboratoře - Laboratoř analytické biochemie a metabolomiky
Oddělení biochemie a fyziologie
Entomologický ústav
+420 387775286 +420 723 648 892
www.bclab.eu
simek@bclab.eu
Analytická chemie a biochemie biologicky aktivních látek, profilování metabolitů, metabolomické přístupy|Analytical chemistry and biochemistry of biol. active compounds, metabolite profiling, metabolomic approaches

Celkem nalezeno: 260 záznamů
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Kučera L.,
Moos M.,
Štětina T.,
Korbelová J.,
Vodrážka P.,
Des Marteaux L. E.,
Grgac R.,
Hůla P.,
Rozsypal J., Faltus M., Šimek P., Sedlacek R.,
Košťál V. (2022) A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva. Journal of Experimental Biology
225: jeb243934.
DOI: http://www/doi:10.1242/jeb.243934 |
Moos M.,
Korbelová J.,
Štětina T.,
Opekar S., Šimek P.,
Grgac R.,
Košťál V. (2022) Cryoprotective metabolites are sourced from both external diet and internal macromolecular reserves during metabolic reprogramming for freeze tolerance in drosophilid fly, Chymomyza costata. Metabolites
12: 163.
DOI: https://doi.org/10.3390/ metabo12020163 |
Vrba P.,
Sucháčková Bartoňová A., Andres M.,
Nedvěd O., Šimek P.,
Konvička M. (2022) Exploring cold hardiness within a butterfly clade: supercooling ability and polyol profiles in European Satyrinae. Insects
13: article number: 369.
DOI: 10.3390/insects13040369 |
Zahradníčková H., Opekar S., Řimnáčová L., Šimek P., Moos M. (2022) Chiral secondary amino acids, their importance, and methods of analysis. Amino Acids Early View: DOI: 10.1007/s00726-022-03136-6 |
Gäde G., Šimek P., Marco H. (2021) Biochemically identified neuropeptides in a caddisfly (Trichoptera) and a pygmy mole cricket (Orthoptera: Caelifera: Tridactyloidea). Archives of Insect Biochemistry & Physiology
106: e21778.
DOI: 10.1002/arch.21778 |
Gerber L., Kresse J.-C., Šimek P.,
Berková P., Overgaard J. (2021) Cold acclimation preserves hindgut reabsorption capacity at low temperature in a chill-susceptible insect, Locusta migratoria. Comparative Biochemistry and Physiology, Part A
252: article number: 110850.
DOI: 10.1016/j.cbpa.2020.110850 |
Nupur , Kuzma M., Hájek J., Hrouzek P., Gardiner A.T., Lukeš M.,
Moos M., Šimek P., Koblížek M. (2021) Structure elucidation of the novel carotenoid gemmatoxanthin from the photosynthetic complex of Gemmatimonas phototrophica AP64. Scientific Reports
11: article number: 15964.
DOI: 10.1038/s41598-021-95254-6 |
Opekar S., Kvíčala J.,
Moos M., Pejchal V., Šimek P. (2021) Mechanism of alkyl chloroformate-mediated esterification of carboxylic acids in aqueous media. Journal of Organic Chemistry
86: 16293-16299.
DOI: 10.1021/acs.joc.1c01546 |
Opekar S., Kvíčala J., Moos M., Pejchal V., Šimek P. (2021) Mechanism of the Alkyl Chloroformate Mediated Esterification of Carboxylic Acids in Aqueous Media. Conference: 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry – Liblice 2021, 3-6 November 2021 |
Opekar S.,
Zahradníčková H.,
Vodrážka P.,
Řimnáčová L., Šimek P.,
Moos M. (2021) A chiral GC-MS method for analysis of secondary amino acids after heptafluorobutyl chloroformate & methylamine derivatization. Amino Acids
53: 347–358.
DOI: 10.1007/s00726-021-02949-1 |
Řimnáčová L.,
Moos M.,
Opekar S.,
Vodrážka P., Pejchal V., Mráz J., Šimek P. (2021) Ethyl chloroformate mediated gas chromatographic-mass spectrometric biomonitoring of acidic biomarkers of occupational exposure and endogenous metabolites in human urine. Journal of Chromatography A
1656: article number: 462547.
DOI: 10.1016/j.chroma.2021.462547 |
Škodová-Sveráková I.,
Záhonová K.,
Juricová V., Danchenko M.,
Moos M., Baráth P.,
Prokopchuk G.,
Butenko A., Lukáčová V., Kohútová L., Bučková B.,
Horák A.,
Faktorová D., Horváth A., Šimek P.,
Lukeš J. (2021) Highly flexible metabolism of the marine euglenozoan protist /Diplonema papillatum/. BMC Biology
19: 251.
DOI: 10.1186/s12915-021-01186-y Dokumenty ke stažení: Skodova-Sverakova_2021_BMCBiol (pdf) |
Gäde G., Šimek P., Marco H. (2020) The adipokinetic peptides in Diptera: structure, function, and evolutionary trends. Frontiers in Endocrinology
11: article number: 153.
DOI: 10.3389/fendo.2020.00153 |
Heneberg P.,
Jegorov A., Šimek P. (2020) Peroral administration of beauverolides allows their transfer to the peripheral blood and urine. CyTA - Journal of Food
18: 644-652.
DOI: 10.1080/19476337.2020.1809525 |
Marco H., Šimek P., Gäde G. (2020) Unique members of the adipokinetic hormone family in butterflies and moths (Insecta, Lepidoptera). Frontiers in Physiology
11: article number: 614552.
DOI: 10.3389/fphys.2020.614552 |
Potts L.J.,
Košťál V., Šimek P., Teets N. M. (2020) Energy balance and metabolic changes in an overwintering wolf spider, Scizocosa stridulans. Journal of Insect Physiology
126: 104112.
DOI: 10.1016/j. jinsphys.2020.104112 |
Sam K., Koane B.,
Sam L.,
Mrázová A.,
Segar S. T.,
Volf M.,
Moos M., Šimek P., Sisol M.,
Novotný V. (2020) Insect herbivory and herbivores of Ficus species along a rain forest elevational gradient on Papua New Guinea. Biotropica
52: 263-276.
DOI: 10.1111/btp.12741 |
Šimčíková D., Tůma P.,
Jegorov A., Šimek P., Heneberg P. (2020) Rapid methods for the separation of natural mixtures of beauverolides cholesterol acyltransferase inhibitors, isolated from the fungus Isaria fumosorosea. Journal of Separation Science
43: 962-969.
DOI: 10.1002/jssc.201901084 |
Škodová-Sveráková I.,
Prokopchuk G.,
Pena Diaz C.,
Záhonová K.,
Moos M., Horváth B., Šimek P.,
Lukeš J. (2020) Unique Dynamics of Paramylon Storage in the Marine Euglenozoan Diplonema papillatum. Protist
171: article number 125717 (publ. April 2020).
DOI: 10.1016/j.protis.2020.125717 Dokumenty ke stažení: Škodová-Sveráková_2020_Protist (pdf) |
Gäde G., Šimek P., Marco H. (2019) Structural diversity of adipokinetic hormones in the hyperdiverse coleopteran Cucujiformia. Archives of Insect Biochemistry and Physiology
102: article number: e21611.
DOI: 10.1002/arch.21611 |