prof. RNDr. Daniel Růžek, Ph.D.
Research Scientist - Laboratory of Arbovirology
Disease Vectors and Pathogens
Institute of Parasitology
+420 38777 5145
ruzekd@paru.cas.cz
316
Research interests
Education
Postgraduate Courses
Employment
Research Internships
Professional Associations
Honors
Books
Book Chapters
5 most important impacted publications:
Medical Virology
Faculty of Science, University of South Bohemia
Pathogenesis of Viral Infections
Faculty of Science, Masaryk University
Total found: 166 records
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Anastasina M., Füzik T., Domanska A., Pulkkinen L.I.A., Šmerdová L., Formanová P.P.,
Straková P., Nováček J., Růžek D., Plevka P., Butcher S.J. (2024) The structure of immature tick-borne encephalitis virus supports the collapse model of flavivirus maturation Science Advances
10: eadl1888.
DOI: 10.1126/sciadv.adl1888 |
Bae J., Bednář P., Zhu R., Bong C., Bak M.S., Stainer S., Kim K., Lee J., Yoon C., Lee Y., Ojowa O.T., Lehner M., Hinterdorfer P., Růžek D., Park S., Oh Y.J. (2024) Mechanisms of plasma ozone and UV-C sterilization of SARS-CoV-2 explored through atomic force microscopy ACS Applied Materials & Interfaces
16: 49176-49185.
DOI: 10.1021/acsami.4c11057 |
Cervantes Rincón T., Kapoor T., Keeffe J.R., Simonelli L., Hoffmann H.H., Agudelo M., Jurado A., Peace A., Lee Y.E., Gazumyan A., Guidetti F., Cantergiani J., Cena B., Bianchini F., Tamagnini E., Moro S.G.,
Svoboda P., Costa F., Reis M.G., Ko A.I., Fallon B.A., Avila-Rios S., Reyes-Téran G., Rice C.M., Nussenzweig M.C., Bjorkman P.J., Růžek D., Varani L., MacDonald M.R. (2024) Human antibodies in Mexico and Brazil neutralizing tick-borne flaviviruses Cell Reports
143: 114298.
DOI: 10.1016/j.celrep.2024.114298 |
Fajfr M., Pajer P., Růžek D., Sleha R., Janovska S., Bohonek M., Kabickova H., Kubíčková P., Štefánik M.,
Straková P., Bostik P. (2024) Multicentric evaluation of sensitivity of eight commercial anti-SARS-CoV-2 antibody assays and their correlation to virus neutralization titers in seropositive subjects Scientific Reports
14: 1421.
DOI: 10.1038/s41598-024-51968-x |
Fialová T., Vaculovicova M., Štefánik M., Mravec F., Burešová M., Vodova M., Rypar T., Růžek D., Hynek D., Cihalova K., Bacovsky J., Ferus M., Nejdl L. (2024) Light-triggered reactions in a new "light" of nanoparticles engineering Journal of Photochemistry and Photobiology A-Chemistry
454: 115667.
DOI: 10.1016/j.jphotochem.2024.115667 |
Fořtová A.,
Straková P., Haviernik J., Svoboda P., Bartonička T., Kvičerová J., Růžek D.,
Salát J. (2024) Brno loanvirus (BRNV) in bats inhabiting the urban area of Brno, Czech Republic Infection, Genetics and Evolution
121: 105604.
DOI: 10.1016/j.meegid.2024.105604 |
Gervais A., Marchal A.,
Fořtová A.,
Beránková M., Krbková L., Pýchová M.,
Salát J., Zhao S., Kerrouche N., Le Voyer T., Stiasny K., Raffl S., Schieber Pachart A., Fafi-Kremer S., Gravier S., Robbiani D.F., Abel L., MacDonald M.R., Rice C.M., Weissmann G., Kamal Eldin T., Robatscher E., Erne E.M., Pagani E., Borghesi A., Puel A., Bastard P., Velay A., Martinot M., Hansmann Y., Aberle J.H., Růžek D., Cobat A., Zhang S.Y., Casanova J.L. (2024) Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalitis in ∼10% of patients Journal of Experimental Medicine
221: e20240637.
DOI: 10.1084/jem.20240637 |
Holoubek J.,
Salát J., Kotouček J., Kastl T.,
Vancová M., Huvarová I., Bednář P., Bednářová K., Růžek D., Renčiuk D.,
Eyer L. (2024) Antiviral activity of porphyrins and porphyrin-like compounds against tick-borne encephalitis virus: blockage of the viral entry/fusion machinery by photosensitization-mediated destruction of the viral envelope Antiviral Research
221: 105767.
DOI: 10.1016/j.antiviral.2023.105767 |
Prančlová V.,
Hönig V.,
Zemanová M., Růžek D.,
Palus M. (2024) Robust CXCL10/IP-10 and CCL5/RANTES production induced by tick-borne Encephalitis virus in human brain pericytes despite weak infection International Journal of Molecular Sciences
25: 7892.
DOI: 10.3390/ijms25147892 |
Růžek D., Kaucká K. (2024) A brief tale of two pioneering moments: Europe's first discovery of Tick-Borne Encephalitis (TBE) virus beyond the Soviet Union and the largest alimentary TBE outbreak in history Ticks and Tick-borne Diseases
15: 102314.
DOI: 10.1016/j.ttbdis.2024.102314 |
Šimečková P., Slavík J., Fořtová A., Huvarová I., Králiková L., Štefánik M.,
Svoboda P., Růžek D., Machala M. (2024) Tick-borne encephalitis virus modulates sphingolipid and phospholipid metabolism in infected human neuronal cells Microbes and Infection
26: 105303.
DOI: 10.1016/j.micinf.2024.105303 |
Vojnikova M., Sukupová M., Štefánik M.,
Straková P., Haviernik J., Kapolkova K., Gruberova E., Raskova K., Michalkova H., Švec P., Kudlickova M.P., Huvarová I., Růžek D.,
Salát J., Pekarik V.,
Eyer L., Heger Z. (2024) Nanoformulation of the Broad-Spectrum Hydrophobic Antiviral Vacuolar ATPase Inhibitor Diphyllin in Human Recombinant H-ferritin International Journal of Nanomedicine
19: 3907–3917.
DOI: 10.2147/IJN.S452119 |
Zimna M., Brzuska G.,
Salát J., Růžek D., Krol E. (2024) Influence of adjuvant type and route of administration on the immunogenicity of Leishmania-derived tick-borne encephalitis virus-like particles - A recombinant vaccine candidate Antiviral Research
228: 105941.
DOI: 10.1016/j.antiviral.2024.105941 |
Bianchini F., Crivelli V., Abernathy M.E., Guerra C.,
Palus M., Muri J., Marcotte H., Piralla A., Pedotti M. , de Gasparo R., Simonelli L., Matkovic M., Toscano C., Biggiogero M., Calvaruso V.,
Svoboda P., Cervantes Rincón T., Fava T., Podešvová L., Shanbhag A.A., Celoria A., Sgrignani J., Štefánik M.,
Hönig V.,
Prančlová V., Michalcikova T., Procházka J., Guerrini G., Mehn D., Ciabattini A., Abolhassani H., Jarrossay D., Uguccioni M., Medaglini D., Pan-Hammarström Q., Calzolai L., Fernandez D. , Baldanti F., Franzetti-Pellanda A., Garzoni C., Sedlacek R., Růžek D., Varani L., Cavalli A., Barnes C.O., Robbiani D.F. (2023) Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein Science Immunology
8: eade0958.
DOI: 10.1126/sciimmunol.ade0958 |
Brzuska G., Zimna M., Baranska K., Szewczyk B.,
Straková P., Růžek D. (2023) The influence of adjuvant type on the immunogenicity of RBD/N cocktail antigens as a vaccine candidate against SARS-CoV-2 Virus Microbiology Spectrum
18: e0256422.
DOI: 10.1128/spectrum.02564-22 |
Chiffi G., Grandgirard D., Leib S.L., Chrdle A., Růžek D. (2023) Tick-borne encephalitis: a comprehensive review of the epidemiology, virology, and clinical picture Reviews in Medical Virology
33: e2470.
DOI: 10.1002/rmv.2470 |
Eyer L., Seley-Radtke K., Růžek D. (2023) New directions in the experimental therapy of tick-borne encephalitis Antiviral Research
210: 105504.
DOI: 10.1016/j.antiviral.2022.105504 |
Fořtová A., Barkhash A.V., Pýchová M., Krbková L.,
Palus M.,
Salát J., Růžek D. (2023) Genetic polymorphisms in innate immunity genes influence predisposition to tick-borne encephalitis Journal of NeuroVirology
29: 699–705.
DOI: 10.1007/s13365-023-01182-8 |
Fořtová A.,
Hönig V.,
Salát J.,
Palus M., Pýchová M., Krbková L., Barkhash A.V., Kříha M.F., Chrdle A., Lipoldová M., Růžek D. (2023) Serum matrix metalloproteinase-9 (MMP-9) as a biomarker in paediatric and adult tick-borne encephalitis patients Virus Research
324: 199020.
DOI: 10.1016/j.virusres.2022.199020 |
Holoubek J.,
Salát J., Kotouček J., Kastl T.,
Vancová M., Huvarová I., Bednář P., Bednářová K., Růžek D., Renčiuk D.,
Eyer L. (2023) Antiviral activity of porphyrins and porphyrin-like compounds against tick-borne encephalitis virus: blockage of the viral entry/fusion machinery by photosensitization-mediated destruction of the viral envelope Antiviral Research
221: 105767.
DOI: 10.1016/j.antiviral.2023.105767 |