prof. RNDr. Libor Grubhoffer, CSc., dr. h. c. mult.
BC Director
Biology Centre CAS
Research Scientist - Laboratory of Molecular Ecology of Vectors and Pathogens
Disease Vectors and Pathogens
Institute of Parasitology
+420 387775050, +420 387775456
liborex@paru.cas.cz
libor.grubhoffer@bc.cas.cz
212, 312
Published a total of 70 scientific articles, 62 papers at conferences and 16 invited lectures. Member of the editorial board of Folia Parasitologica and of several scientific societies, and scienticic counciles of the University of South Bohemia in České Budějovice (USB), the Institute of Entomology AS CR, Institute of Plant Molecular Biology AS CR, Institute of Landscape Ecology AS CR, the Faculty of Biological Sciences USB, and the Institute of Physical Biology USB.Research interests
University Education
Postgraduate Study
Employment History
Scientific Background, Research Experience
Long-term Study Stays Abroad and International Collaborations
Biochemistry
Faculty of Science, University of South Bohemia
Basic Laboratory Course in Biochemistry
Faculty of Science, University of South Bohemia
Biochemistry I
Faculty of Science, University of South Bohemia
Biochemistry 1
Faculty of Science, University of South Bohemia
Biochemistry 2
Faculty of Science, University of South Bohemia
Biological Chemistry - Bachelor Seminar
Faculty of Science, University of South Bohemia
Developmental and Comparative Biochemistry (for Biological Chemistry)
Faculty of Science, University of South Bohemia
Glycobiochemistry (for Biological Chemistry)
Faculty of Science, University of South Bohemia
Laboratory practise from Biochemistry
Faculty of Science, University of South Bohemia
Laboratory Course in Biochemistry
Faculty of Science, University of South Bohemia
Advanced Laboratory Course in Biochemistry
Faculty of Science, University of South Bohemia
Seminar in Advanced Biological Chemistry
Faculty of Science, University of South Bohemia
Seminar in Advanced Biological Chemistry II
Faculty of Science, University of South Bohemia
Total found: 156 records
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Mašková H.,
Doudová L.,
Lieskovská J., Grubhoffer L., Štěrba J. (2024) Characterization of stem cell-derived langerhans-like cells: new model immune cells for tick-borne encephalitis virus infection studies Stem Cell Reviews and Reports
20: 1367–1369.
DOI: 10.1007/s12015-024-10722-6 |
Mazuecos L., Contreras M., Kasaija P.D., Manandhar P., Grąźlewska W., Guisantes-Batan E., Gomez-Alonso S., Deulofeu K., Fernandez-Moratalla I., Rajbhandari R.M.,
Sojka D., Grubhoffer L., Karmacharya D., Gortazar C., de la Fuente J. (2023) Natural Clerodendrum-derived tick repellent: learning from Nepali culture Experimental and Applied Acarology
90: 83–98.
DOI: 10.1007/s10493-023-00804-4 |
Rudenko N.,
Golovchenko M.,
Horák A., Grubhoffer L., Mongodin E.F., Fraser C.M., Qiu W., Luft B., Morgan R.G., Casjens S.R., Schutzer S. (2023) Genomic confirmation of Borrelia garinii in the USA Emerging Infectious Diseases
29: 1.
DOI: 10.3201/eid2901.220930 |
Grubhoffer L., Mašková H., Doudová L., Selinger M., Věchtová P., Štěrba J. (2022) Verification of markers for early stage of tick-borne encephalitis infection in vitro and in vivo Febs Open Bio
12: 164–164 Supl. 1, Special Issue.
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Hrnková J.,
Golovchenko M., Musa A.S., Needham T., Italiya J., Ceacero F., Kotrba R., Grubhoffer L.,
Rudenko N., Černý J. (2022) Borrelia spirochetes in European exotic farm animals Frontiers in Veterinary Science
9: 996015.
DOI: 10.3389/fvets.2022.996015 |
Selinger M., Novotný R., Sýs J., Roby J.A.,
Tykalová H., Ranjani G.S.,
Vancová M., Jaklová K., Kaufman F., Bloom M.E., Zdráhal Z., Grubhoffer L., Forwood J.K., Hrabal R., Rumlová M., Štěrba J. (2022) Tick-borne encephalitis virus capsid protein induces translational shut-off as revealed by its structural-biological analysis Journal of Biological Chemistry
298: 102585.
DOI: 10.1016/j.jbc.2022.102585 |
Selinger M., Věchtová P., Tykalová H., Ošlejšková P., Rumlová M., Štěrba J., Grubhoffer L. (2022) The analysis of differential expression and interactions of host and virus derived RNAs in human primary neural cells reveals candidate effectors of TBEV-induced neuropathogenesis Febs Open Bio
12: 164–164 Supl. 1, Special Issue.
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Selinger M., Věchtová P.,
Tykalová H., Ošlejšková P., Rumlová M., Štěrba J., Grubhoffer L. (2022) Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors Computational and Structural Biotechnology Journal
20: 2759-2777.
DOI: 10.1016/j.csbj.2022.05.052 |
Černý J.,
Elsterová J.,
Růžek D., Grubhoffer L. (2021) Vertebrate viruses in polar ecosystems. In: G. di Prisco, G.M.E. Howell, J. Elster, A.H.L. Huiskes (Eds.). Life in Extreme Environments: Insights in Biological Capability
126-147.
DOI: 9781108724203 |
de la Fuente J., Armas O., Sánchez-Rodríguez L., Gortazar C., Lukashev A.N.,
Kotsyfakis M., Grubhoffer L. (2021) Citizen science initiative points at childhood BCG vaccination as a risk factor for COVID-19 Transboundary and Emerging Diseases
6: 3114–3119.
DOI: 10.1111/tbed.14097 |
Hejduk L., Rathner P.,
Strnad M., Grubhoffer L., Štěrba J.,
Rego R. O. M., Muller N. (2021) Resonance assignment and secondary structure of DbpA protein from the European species, Borrelia afzelii. Biomolecular NMR Assignments
15: 415–420.
DOI: 10.1007/s12104-021-10039-2 |
Hrnková J., Schneiderová I.,
Golovchenko M., Grubhoffer L.,
Rudenko N., Černý J. (2021) Role of Zoo-Housed Animals in the Ecology of Ticks and Tick-Borne Pathogens—A Review Pathogens
10: 210.
DOI: 10.3390/pathogens10020210 |
Kotsarenko K.,
Věchtová P., Wimmerová M.,
Štěrba J., Grubhoffer L. (2021) Possible ways for manipulating the gene expression in Ixodes ricinus ticks FEBS Open Bio
11: 141.
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Oh Y.J.,
Strnad M.,
Vancová M., Hain L., Salo J., Grubhoffer L.,
Nebesářová J., Hytoenen J., Hinterdorfer P.,
Rego R. O. M. (2021) 13 th EBSA congress, July 24-28, 2021, Vienna, Austria: Nanomechanical mechanisms of Borrelia interactions with extracellular matrix European Biophysics Journal with Biophysics Letters
50: S59.
DOI: 10.1007/s00249-021-01558-w |
Rudenko N., Grubhoffer L.,
Golovchenko M. (2021) Climate impact on Lyme borreliosis and its causative agents In: P. Nuttall (Ed.) Climate, Ticks and Disease
chapter 49.
DOI: 9781789249637 |
Rusanov A.L., Kozhin P.M., Tikhonova O.V., Zgoda V.G., Loginov D.S., Chlastáková A.,
Selinger M., Štěrba J., Grubhoffer L., Luzgina N.G. (2021) Proteome Profiling of PMJ2-R and Primary Peritoneal Macrophages International Journal of Molecular Sciences
22: 6323.
DOI: 10.3390/ijms22126323 |
Strnad M., Oh Y.J.,
Vancová M., Hain L., Salo J., Grubhoffer L.,
Nebesářová J., Hytönen J., Hinterdorfer P.,
Rego R. O. M. (2021) Nanomechanical mechanisms of Lyme disease spirochete motility enhancement in extracellular matrix Communications Biology
4: 268 .
DOI: 10.1038/s42003-021-01783-1 |
Věchtová P., Füssy Z., Štěrba J., Grubhoffer L. (2021) Expression of glycan biosynthetic enzymes and glycan-binding proteins in Ixodes ricinus tick life stages FEBS Open Bio
11: 498.
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Černý J., Lynn G., Hrnková J.,
Golovchenko M.,
Rudenko N., Grubhoffer L. (2020) Management Options forIxodes ricinus-AssociatedPathogens: A Review of Prevention Strategies International Journal of Environmental Researchand Public Health
17: 1830.
DOI: 10.3390/ijerph17061830 |
Helmová R.,
Hönig V.,
Tykalová H.,
Palus M., Bell-Sakyi L., Grubhoffer L. (2020) Tick-borne encephalitis virus adaptation in different host environments and existence of quasispecies Viruses
12: 902.
DOI: 10.3390/v12080902 |